Set in near-future inland Florida, Teenage Euthanasia centers around the owners of Tender Endings funeral home, the Fantasy Family Grandma Baba, her adult children Uncle Pete and Trophy, and Trophy's teenage daughter, Euthanasia (Annie), a name accidentally given to her during the time of Trophy's own unbearable suffering. Back when Trophy was a teen herself; she ran away from home after giving birth to Annie, leaving her newborn to be raised by Baba and Uncle Pete. Now, 15 years later, Trophy returns to Tender Endings...as a corpse, for burial. When a bolt of lightning strikes Baba's homemade embalming fluid and one of Annie's tears, Trophy comes back from the dead. As a resurrected woman, Trophy has a variety of quasi-useful death powers. But more importantly, she has a second chance at unplanned parenthood.

皮克斯动画工作室的首部原创剧集讲述了八个不同角色的交织故事，他们每个人都在为他们的大型冠军垒球比赛做准备。该系列以非常有趣、非常感应和独特的动画视角揭示了每个角色的真实感受——不安的的孩子们、直升机式的父母，甚至是痴情的裁判。

一对年轻的布鲁克林夫妇前往北部，他们断开了手机，与自己重新建立联系。由于切断了电子设备，他们错过了地球正遭受攻击的消息。

中年单身程序设计师马特决定要当父亲，通过面试找到26岁的咖啡店服务生安娜代孕生子。安娜因与家人关系僵化，搬至旧金山，她希望通过代孕能获得供自己完成学业的钱。在孕期马特积极介入安娜的生活，事无巨细，安娜也逐渐接受马特的亲密，彼此敞开心扉，建立了一段不太寻常的友谊。